About 1 result found for searched term "SEL24-B489" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13428 | SEL24-B489 | Pim |
| Sel24-b489 is a novel pan-PIM inhibitor that induces apoptosis in DLBCL cell lines at low/submicromol concentrations and has shown activity in xenotransplantation models. It is an effective oral PIM and FLT3-ITD dual inhibitor with Kds of 2, 2 and 3 nM against PIM1, PIM2 and PIM3, respectively. | ||
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